Mesenchymal Stem Cells And Autism

Among the stem cell population mesenchymal stem cells mscs show probably best potential good results in medical research.

Mesenchymal stem cells and autism.

In fact one recent study using a mouse strain bred to have autistic like symptoms showed that transplantation of mesenchymal stem cells resulted in a reduction in stereotypical behaviors a decrease in cognitive rigidity and an improvement in social behavior. Why treat autism with mesenchymal stem stromal cells msc. Umbilical cord mesenchymal stem cell infusions were safe and generally well tolerated. Due to the particular immune and neural dysregulation observed in asds.

The primary sources of the msc in clinical trials are bone marrow fat tissue and umbilical cord tissue 24 27. Based on laboratory studies and clinical trials for other conditions msc are the leading cell type used to treat auto immune disorders and inflammation 28 30. To the authors knowledge this is the first single arm phase i ii clinical trial of repeated dose umbilical cord mesenchymal stem cells administration in children diagnosed with autism spectrum disorder asd.